gene 2,794 words KG: SETD1A
Contents

SETD1A Gene

🧬 Gene Info
Gene SymbolSETD1A
Full NameSET Domain Containing 1A, Histone Lysine Methyltransferase
Chromosome16p11.2
Protein TypeTransferase
Functionencodes a histone H3 lysine 4 (H3K4) methyltransferase that is the catalytic subunit of the SETD1A/COMPASS complex.
UniProt IDO15047
Ensembl IDENSG00000099381
OMIM611052
GeneCardsSETD1A
Human Protein AtlasSETD1A
Associated Diseasesschizophrenia
InteractionsANK3, CACNA1G, GENES, KMT2A, KMT2B, KMT2D
KG Connections28 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.72

Related Analyses (2)

Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Brain Connectivity-Targeted tACS Trial in Early AD
clinical · proposed · Score: 0.51
tACS Connectivity Trial in Early Alzheimer's
clinical · proposed · Score: 0.40
Brain Connectivity-Targeted tACS Trial in Early AD
clinical · proposed · Score: 0.40
DLB Cognitive Fluctuation Mechanism Experiment
clinical · proposed · Score: 0.40
Migraine Cortical Hyperexcitability and Alzheimer's Disease
clinical · proposed · Score: 0.40

See Also (8)

Neurodegeneration
disease · KG edge: implicated_in
Genes
index · KG edge: inhibits
CACNA1G Gene
gene · KG edge: inhibits
GAIN Gene - GABA-A Receptor Associated Protein Like 2
gene · KG edge: expressed_in
KMT2A — lysine methyltransferase 2A
gene · KG edge: inhibits

Knowledge Graph (12 edges)

SETD1A expressed_in GAIN
SETD1A inhibits KMT2B
SETD1A inhibits SHANK3
SETD1A inhibits KMT2D
SETD1A inhibits CACNA1G
SETD1A inhibits KMT2A
KMT2A inhibits SETD1A
SHANK3 inhibits SETD1A
CACNA1G inhibits SETD1A
GAIN expressed_in SETD1A

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