gene 578 words KG: KMT2B
Contents

KMT2B — lysine methyltransferase 2B

🧬 Gene Info
Gene SymbolKMT2B
Full NameMLL2 (Mixed-Lineage Leukemia 2) / MLL4
Aliaseslysine methyltransferase 2B
Protein FamilySET1/MLL COMPASS Family
Protein TypeTransferase
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionbrain tissue
Subcellular LocalizationNucleus
Molecular Weight445 kDa
PathwaysFMN-induced Anti-inflammatory Effect
UniProt IDQ9UMN6
GeneCardsKMT2B
Human Protein AtlasKMT2B
Alzheimer's DiseaseAltered expression and function contributes to epigenetic dysregulation of neuronal survival genes
Parkinson's DiseaseMay affect dopaminergic neuron survival through transcriptional mechanisms
Associated DiseasesALS, Alzheimer
InteractionsANK3, CACNA1G, GENES, KMT2A, KMT2D, NF-ΚB
KG Connections57 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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