| Gene Symbol | KAT8 |
| Chromosome | 16q24.1 |
| Protein Type | Transferase |
| Function | KAT8/MOF is a highly conserved histone acetyltransferase belonging to the MYST family (MOZ, YBF2/SAS3, SAS2, TIP60). |
| Molecular Weight | 52 kDa |
| Amino Acids | 458 aa |
| Pathways | NF-κB |
| UniProt ID | Q9H7Z6 |
| NCBI Gene ID | 84144 |
| Ensembl ID | ENSG00000103510 |
| OMIM | 609912 |
| GeneCards | KAT8 |
| Human Protein Atlas | KAT8 |
| Primary target | H4K16ac — the hallmark modification that prevents chromatin compaction |
| Secondary targets | H4K5, H4K8, H2AK5, H2BK120 |
| Associated Diseases | Neurodegeneration, Parkinson, Tumor |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACAT1, AMPK, ATG, CALCOCO2, CBP, CREB |
| KG Connections | 207 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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