| Gene Symbol | ENDOG |
| Full Name | Endonuclease G, Mitochondrial |
| Aliases | Endonuclease G |
| Chromosome | 9q34.11 |
| Function | ENDOG (Endonuclease G) is a mitochondrial nuclease that plays important roles in both mitochondrial DNA maintenance and apoptosis. |
| Primary Expression | most tissues, with high expression in tissues containing high numbers of mitochondria |
| Subcellular Localization | , linking it to stress-response kinase cascades including JNK and p38 MAPK pathways. Additionally, ENDOG participates in |
| Molecular Weight | 30 kDa |
| Amino Acids | 27 aa |
| Pathways | Akt, Apoptosis, Autophagy, Mitophagy, Mtor |
| UniProt ID | [O95071](https://www.uniprot.org/uniprot/O95071) |
| Ensembl ID | ENSG00000167136 |
| OMIM | 601060 |
| GeneCards | ENDOG |
| Human Protein Atlas | ENDOG |
| Associated Diseases | neurodegeneration |
| Interactions | ACETYL-COA, AKT, AND, APOPTOSIS, AUTOPHAGY, BIP |
| KG Connections | 71 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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