| Gene Symbol | EIF2AK2 |
| Full Name | Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2 |
| Aliases | Protein Kinase R |
| Chromosome | 2p22.2 |
| Protein Family | eIF2α kinase family |
| Protein Type | Serine/Threonine Kinase |
| Function | is a serine/threonine kinase that serves as a critical sensor of cellular stress and a key activator of the integrated stress response (ISR). |
| Subcellular Localization | EIF2AK2 localizes primarily to the cytoplasm: |
| Amino Acids | 551 aa |
| Exons | 16 |
| Pathways | NF-κB |
| UniProt ID | [P19589](https://www.uniprot.org/uniprot/P19589) |
| Ensembl ID | ENSG00000055332 |
| OMIM | 603013 |
| GeneCards | EIF2AK2 |
| Human Protein Atlas | EIF2AK2 |
| Associated Diseases | AD, Als, Alzheimer, Alzheimer's disease, AMI, disease |
| Interactions | A2M, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND, APH1B |
| KG Connections | 148 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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