gene 524 words KG: DRP1
Contents

DRP1 Gene - Dynamin 1-Like Protein

🧬 Gene Info
Gene SymbolDRP1
Protein TypeEnzyme
FunctionThe DRP1 gene encodes a 736-amino acid GTPase
PathwaysApoptosis, Autophagy, Cell Cycle, Complement, Dna Methylation
Ensembl IDENSG00000141971
GeneCardsDRP1
Human Protein AtlasDRP1
Mitochondrial fissionMediates scission of mitochondrial outer membrane
GTP hydrolysisSelf-assembles into rings that hydrolyze GTP to drive membrane constriction
Associated DiseasesAD, Aging, ALI, Als, Alzheimer
Known Drugs/Compoundsginsenoside Re, Ginsenoside Re, Mdivi-1, Palmitic Acid, propionic acid, Rg1
InteractionsABCD3, ABCG2, Actin, ADORA2A, AGING, AKT
KG Connections1692 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (43)

RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
← Prevpg 3/3

Related Analyses (18)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

See Also (8)

ABCD3 Gene
gene · KG edge: interacts_with
ABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: activates
ADORA2A Gene
gene · KG edge: interacts_with
AKT1 Gene
gene · KG edge: activates
Accelerating Medicines Partnership for Alzheimer's Dise
institution · KG edge: implicated_in

Knowledge Graph (12 edges)

CAT interacts_with DRP1
OPTN interacts_with DRP1
CANX interacts_with DRP1
LGALS3 interacts_with DRP1
CALCOCO2 interacts_with DRP1
G3BP1 interacts_with DRP1
PEX3 interacts_with DRP1
SQSTM1 interacts_with DRP1
BCL2 interacts_with DRP1
LMNA interacts_with DRP1

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