Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PALMITIC ACID: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | PALMITIC ACID |
graph TD
PALMITIC_ACID[PALMITIC ACID]
PALMITIC_ACID -->|inhibits| autophagy[autophagy]
PALMITIC_ACID -->|causes| mitochondrial_fragmentation[mitochondrial fragmentation]
PALMITIC_ACID -->|activates| STING1[STING1]
PALMITIC_ACID -->|disrupts| PKD2_BECN1_complex[PKD2-BECN1 complex]
PALMITIC_ACID -->|downregulates| MFN2[MFN2]
PALMITIC_ACID -->|inhibits| Lipophagy[Lipophagy]
PALMITIC_ACID -->|phosphorylates| SQSTM1[SQSTM1]
PALMITIC_ACID -->|activates| JNK[JNK]| Target | Relation | Type | Str |
|---|---|---|---|
| lysosomal function | associated_with | process | 0.95 |
| autophagy | inhibits | process | 0.95 |
| mitochondrial fragmentation | causes | phenotype | 0.94 |
| autophagy | inhibits | process | 0.92 |
| MFN2 | downregulates | protein | 0.90 |
| PKD2-BECN1 complex | disrupts | protein | 0.90 |
| STING1 | activates | protein | 0.90 |
| mitochondrial function | associated_with | process | 0.90 |
| oxidative stress | associated_with | process | 0.90 |
| STING1 | activates | protein | 0.90 |
| TNF-α | activates | protein | 0.85 |
| Mitochondrial Reactive Oxygen Species | causes | phenotype | 0.85 |
| SQSTM1 | phosphorylates | protein | 0.85 |
| JNK | activates | gene | 0.85 |
| Lipophagy | inhibits | process | 0.85 |
| DRP1 | phosphorylates | protein | 0.85 |
| Oligodendrocyte Differentiation | modulates | process | 0.80 |
| DRP1 | modulates | protein | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PALMITIC ACID in their description or question text
No additional research found