gene 1,225 words KG: PEX3
Contents

PEX3 Gene - Peroxisome Biogenesis Factor 3

🧬 Gene Info
Gene SymbolPEX3
Full NamePeroxisome Biogenesis Factor 3
AliasesPage for PEX3 Gene, Page for PEX3 Protein
Functionis a 476-amino acid peroxisomal membrane protein that plays a central role in peroxisome biogenesis.
Molecular Weight52 kDa
Amino Acids476 aa
PathwaysMAPK signaling, Reactive Oxygen Species, apoptosis, apoptosis pathway, autophagy pathway
Ensembl IDENSG00000034693
GeneCardsPEX3
Human Protein AtlasPEX3
Associated DiseasesAD, ALI, Als, Alzheimer, dementia
InteractionsABCD3, Actin, ALS, ALZHEIMER, ALZHEIMER DISEASE, AMBRA1
KG Connections466 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (12)

ATP P2X3 Receptor Neurons
cell · KG edge: activates
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: co_discussed
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: associated_with
ABCD3 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

CAT interacts_with PEX3
OPTN interacts_with PEX3
DNM1L interacts_with PEX3
CANX interacts_with PEX3
LGALS3 interacts_with PEX3
CALCOCO2 interacts_with PEX3
G3BP1 interacts_with PEX3
PEX3 interacts_with SQSTM1
PEX3 interacts_with BCL2
PEX3 interacts_with LMNA

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