| Gene Symbol | DCC |
| Full Name | Deleted in Colorectal Cancer |
| Chromosome | 18q21.2 |
| Protein Type | Receptor |
| Function | DCC is a member of the immunoglobulin superfamily of cell adhesion molecules and functions as the primary receptor for the axon guidance molecule netrin-1. |
| Primary Expression | the developing and adult central nervous system, where it plays essential roles in neuronal axon guidance, cell migration, synapse formation, and syna |
| Amino Acids | 750 aa |
| Pathways | PI3K-AKT-mTOR signaling |
| UniProt ID | [Q9Y266](https://www.uniprot.org/uniprot/Q9Y266) |
| Ensembl ID | ENSG00000187323 |
| OMIM | 120470 |
| GeneCards | DCC |
| Human Protein Atlas | DCC |
| Extracellular Domain | 4 immunoglobulin (Ig) domains and 6 fibronectin type III (FNIII) repeats that mediate netrin-1 binding and cell adhesion |
| Transmembrane Domain | Single pass transmembrane helix |
| Associated Diseases | Als, cancer |
| Interactions | AKT, APOPTOSIS, CANCER, CD44, EPHA4, FGF10 |
| KG Connections | 83 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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