gene 736 words KG: TNC
Contents

TNC Gene

🧬 Gene Info
Gene SymbolTNC
Full NameTenascin C
Chromosome9
FunctionThe TNC gene encodes Tenascin C, a protein expressed in various brain regions including the cerebral cortex, hippocampus, basal ganglia, and cerebellum.
Primary Expressionvarious brain regions including the cerebral cortex, hippocampus, basal ganglia, and cerebellum
PathwaysInflammasome, Nf-Κb
UniProt IDP24821
Ensembl IDENSG00000052850
OMIM187380
GeneCardsTNC
Human Protein AtlasTNC
Associated DiseasesAls, Entheseal new bone formation, Extracellular matrix adhesion force, Fibrosis, Liver fibrosis
Known Drugs/Compoundsmetformin
InteractionsAMPK, AND, APOPTOSIS, ARG1, CANCER, CD44
KG Connections75 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: regulates
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: inhibits
Microglia in Neurodegeneration
entity · KG edge: activates
TLR4 (Redirect)
redirect · KG edge: associated_with

Knowledge Graph (12 edges)

CDKN2A inhibits TNC
TLR4 associated_with TNC
TNC associated_with NTRK2
TNC inhibits PAK1
TNC inhibits WNT7A
TNC inhibits LZTS1
TNC inhibits DCC
TNC inhibits KCNK2
TNC inhibits CD44
TNC inhibits FGF10

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