gene 963 words KG: COL4A1
Contents

COL4A1 Gene

🧬 Gene Info
Gene SymbolCOL4A1
Full NameCollagen Type IV Alpha 1 Chain
Chromosome13q34
Protein FamilyType IV collagen alpha chain family
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionbasement membranes:
Molecular Weight161 kDa
Amino Acids664 aa
Exons52
UniProt IDP02462
NCBI Gene ID1282
Ensembl IDENSG00000187498
OMIM120130
GeneCardsCOL4A1
Human Protein AtlasCOL4A1
Associated DiseasesAging, Als, Alzheimer, Atherosclerosis, Dementia
InteractionsABCB1, APOD, APOPTOSIS, CANCER, CD44, CREBBP
KG Connections82 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Piezoelectric Nanochannel BBB Disruption
Score: 0.52

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

Apoptosis in Neurodegeneration
entity · KG edge: inhibits
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: associated_with
APOC2 Gene
gene · KG edge: associated_with
ATL1
gene · KG edge: associated_with
CD44 - Cell Surface Glycoprotein
gene · KG edge: inhibits

Knowledge Graph (12 edges)

COL4A1 associated_with LZTS1
COL4A1 associated_with APOC2
NOTCH3 contributes_to COL4A1
HTRA1 contributes_to COL4A1
COL4A1 contributes_to OVERVIEW
CDKN2A associated_with COL4A1
TLR4 inhibits COL4A1
TNC inhibits COL4A1
NTRK2 inhibits COL4A1
PAK1 inhibits COL4A1

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