| Gene Symbol | NCF1 |
| Full Name | Neutrophil Cytosolic Factor 1 |
| Chromosome | 7q11.23 |
| Protein Type | Enzyme |
| Function | NCF1 encodes the p47^phox^ subunit, a critical organizer of the NADPH oxidase complex. |
| Primary Expression | microglia, the resident immune cells of the brain |
| Amino Acids | 340 aa |
| Pathways | Apoptosis, Ferroptosis, Toll-Like Receptor |
| UniProt ID | P14598 |
| NCBI Gene ID | 4748 |
| Ensembl ID | ENSG00000158517 |
| OMIM | 608512 |
| GeneCards | NCF1 |
| Human Protein Atlas | NCF1 |
| NADPH oxidase assembly | Essential for NOX2 activation in microglia |
| Associated Diseases | Alzheimer, Diabetes, Inflammation, Neuroinflammation, Parkinson |
| Interactions | ANG, FERROPTOSIS, INFLAMMATION, NRF2, Rb, STING |
| KG Connections | 99 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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