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gene 2,729 words KG: RAC1
Contents

RAC1 Gene

🧬 Gene Info
Gene SymbolRAC1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight21.4 kDa
Amino Acids192 aa
PathwaysApoptosis, Autophagy, Dendritic Spine, Mtor, Nf-Κb
Ensembl IDENSG00000136238
GeneCardsRAC1
Human Protein AtlasRAC1
Associated DiseasesAls, Cancer, Diabetes, Encephalitis, Inflammation
InteractionsACTB, Actin, ACVR1, AKT, AKT1, ALZHEIMER
KG Connections487 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (23)

Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.56CYP46A1 Overexpression Gene Therapy
Score: 0.92AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.81Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75

Related Analyses (12)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archivedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (12)

Apoptosis in Neurodegeneration
entity · KG edge: regulatesAmyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activatesACTB Gene
gene · KG edge: regulatesACVR1 Gene
gene · KG edge: interacts_withAKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

VAV1 activates RAC1
ACTB regulates RAC1
CDC42 regulates RAC1
CASP3 regulates RAC1
SQSTM1 associated_with RAC1
TUBB3 associated_with RAC1
STK11 associated_with RAC1
VIM associated_with RAC1
BECN1 regulates RAC1
HDAC6 associated_with RAC1

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