gene 994 words KG: CLCN7
Contents

CLCN7 Gene

🧬 Gene Info
Gene SymbolCLCN7
Full NameChloride Voltage-Gated Channel 7
Chromosome16p13.3
Protein TypeChannel
Functionis a member of the CLC chloride channel family, which comprises both plasma membrane channels and intracellular voltage-gated chloride channels.
Amino Acids805 aa
UniProt IDP51797
NCBI Gene ID1191
Ensembl IDENSG00000132449
OMIM602727
GeneCardsCLCN7
Human Protein AtlasCLCN7
BoneOsteoclasts — highly expressed, critical for bone resorption
BrainNeurons, particularly in hippocampus, cortex, and substantia nigra
KidneyTubular cells
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsAMPD2, GNAI3, GNPTG, WDR81
KG Connections23 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.95
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: expressed_in
AKT1 Gene
gene · KG edge: expressed_in
AMPD2 — Adenosine Monophosphate Deaminase 2
gene · KG edge: activates
ATG16L1 - Autophagy Related 16 Like 1
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

AKT1 expressed_in CLCN7
AKT expressed_in CLCN7
GNB1 expressed_in CLCN7
AMPD2 activates CLCN7
ATG5 expressed_in CLCN7
MAVS expressed_in CLCN7
TBK1 expressed_in CLCN7
CLCN7 expressed_in RIPK2
CLCN7 expressed_in IFIH1
CLCN7 expressed_in GNAI1

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