gene

ampd2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ampd2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

25Connections

0Hypotheses

0Analyses

20Outgoing

5Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	AMPD2
Full Name	Adenosine Monophosphate Deaminase 2
Aliases	SPG63
Chromosome	1p13.3
Protein Family	AMP deaminase family
Protein Type	Enzyme
Function	catalyzes AMP deamination to IMP
Primary Expression	skeletal muscle, heart, and brain
Molecular Weight	85 kDa
Amino Acids	771 aa
Pathways	mTOR, AMPK
UniProt ID	Q01469
NCBI Gene ID	271
Ensembl ID	ENSG00000116337
OMIM	102771
GeneCards	AMPD2
Human Protein Atlas	AMPD2
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: ampd2 — AlphaFold Q01469 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

AMPD2 — Adenosine Monophosphate Deaminase 2

gene · 1710 words

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Pathway Diagram

graph TD
    AMPD2["AMPD2"]
    AMPD2 -->|"expressed in"| Cardiovascular["Cardiovascular"]
    AMPD2 -->|"expressed in"| ATG5["ATG5"]
    AMPD2 -->|"expressed in"| MAVS["MAVS"]
    AMPD2 -->|"expressed in"| TBK1["TBK1"]
    AMPD2 -->|"activates"| CLCN7["CLCN7"]
    AMPD2 -->|"expressed in"| RIPK2["RIPK2"]
    AMPD2 -->|"expressed in"| IFIH1["IFIH1"]
    AMPD2 -->|"expressed in"| GNAI1["GNAI1"]
    AKT1["AKT1"] -->|"expressed in"| AMPD2
    AUTOPHAGY["AUTOPHAGY"] -->|"expressed in"| AMPD2
    AKT["AKT"] -->|"expressed in"| AMPD2
    GNB1["GNB1"] -->|"expressed in"| AMPD2

Outgoing (20)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:AMPD2	data_in	dataset_row	0.00
Cardiovascular	expressed_in	disease	0.65
Autophagy	expressed_in	pathway	0.60
Wnt	expressed_in	pathway	0.60
Akt	expressed_in	pathway	0.60
ATG5	expressed_in	gene	0.60
MAVS	expressed_in	gene	0.60
TBK1	expressed_in	gene	0.60
CLCN7	activates	gene	0.60
RIPK2	expressed_in	gene	0.60
IFIH1	expressed_in	gene	0.60
GNAI1	expressed_in	gene	0.60
ATG16L1	expressed_in	gene	0.60
GNG2	expressed_in	gene	0.60
WDR81	activates	gene	0.60
GNPTG	activates	gene	0.60
GNAI2	expressed_in	gene	0.60
NOD2	expressed_in	gene	0.60
GNAS	expressed_in	gene	0.60
GNAI3	activates	gene	0.60

Incoming (5)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:AMPD2	data_in	dataset_row	0.00
AUTOPHAGY	expressed_in	gene	0.60
AKT1	expressed_in	gene	0.60
AKT	expressed_in	gene	0.60
GNB1	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ampd2 in their description or question text

No additional research found