concept

FCER1G

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FCER1G: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

28Connections

1Hypotheses

0Analyses

16Outgoing

12Incoming

0Experiments

0Debates

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💡 Concept Info

Name	FCER1G
Key Genes/Proteins	ABCA1, APOE, BIN1, C1QB, CD33, CSF1R
Linked Hypotheses	1 hypotheses

Pathway Diagram

graph TD
    FCER1G[FCER1G]
    FCER1G -->|regulates| IL1B[IL1B]
    FCER1G -->|regulates| JUN[JUN]
    FCER1G -->|regulates| MMP9[MMP9]
    FCER1G -->|regulates| TLR2[TLR2]
    FCER1G -->|regulates| TNF[TNF]
    FCER1G -->|regulates| MS4A6A[MS4A6A]
    FCER1G -->|regulates| SPI1[SPI1]
    FCER1G -->|regulates| MARCKS[MARCKS]
    FCER1G -->|regulates| SQSTM1[SQSTM1]
    FCER1G -->|regulates| HLA[HLA]
    EIF2AK2[EIF2AK2] -->|activates| FCER1G
    CXCL1[CXCL1] -->|regulates| FCER1G
    CXCL8[CXCL8] -->|regulates| FCER1G
    BIN1[BIN1] -->|regulates| FCER1G
    CD33[CD33] -->|regulates| FCER1G
    ABCA1[ABCA1] -->|regulates| FCER1G
    APOE[APOE] -->|regulates| FCER1G
    CTSB[CTSB] -->|regulates| FCER1G
    CTSH[CTSH] -->|regulates| FCER1G
    benchmark_ot_ad_answer_key_FCE[benchmark_ot_ad_answer_key:FCER1G] -->|data_in| FCER1G

Outgoing (16)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:FCER1G	data_in	dataset_row	0.00
Immune Cell Infiltration	associated_with	process	0.80
IL1B	regulates	gene	0.60
JUN	regulates	gene	0.60
MMP9	regulates	gene	0.60
TLR2	regulates	gene	0.60
TNF	regulates	gene	0.60
MS4A6A	regulates	gene	0.60
SPI1	regulates	gene	0.60
TYROBP	associated_with	gene	0.60
MARCKS	regulates	gene	0.60
SQSTM1	regulates	gene	0.60
PGRN	regulates	gene	0.60
HLA	regulates	gene	0.60
microglia	expressed_in	cell_type	0.55
macrophages	expressed_in	cell_type	0.55

Incoming (12)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:FCER1G	data_in	dataset_row	0.00
ABCA1	regulates	gene	0.60
APOE	regulates	gene	0.60
CTSB	regulates	gene	0.60
CTSH	regulates	gene	0.60
EIF2AK2	activates	gene	0.60
CXCL1	regulates	gene	0.60
CXCL8	regulates	gene	0.60
BIN1	regulates	gene	0.60
CD33	regulates	gene	0.60
C1QB	associated_with	gene	0.60
CSF1R	associated_with	gene	0.60

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
FCER1G-Mediated Alternative Immune Signaling	0.480	neurodegeneration	TREM2 Therapeutic Strategy Post-INVOKE-2

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FCER1G in their description or question text

No additional research found