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entity 1,004 words KG: NMDA
Contents

NMDA Receptor

🔬 Protein Info
Gene SymbolNMDA
AliasesGRIN2B, GRIN1
Molecular Weight166 kDa
Pathwaysglutamate signaling, unfolded protein response, oxidative stress response, mitochondrial function, sphingolipid metabolism
GeneCardsNMDA
Human Protein AtlasNMDA
Associated DiseasesALS, Alzheimer, Alzheimer'S Disease, disease, epilepsy, Huntington
Known Drugs/Compoundsmemantine
InteractionsABCA7, AMPA RECEPTOR, AMYLOID, APP, ATP, BAK
KG Connections211 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

Wikipedia

Related Hypotheses (34)

Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78Epigenetic Memory Erasure via TET2 Activation
Score: 0.74Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72Membrane Cholesterol Gradient Modulators
Score: 0.71TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.71Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69Flotillin-1 Stabilization Compounds
Score: 0.68Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65Nucleolar Stress Response Normalization
Score: 0.65Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65Vagal Afferent Microbial Signal Modulation
Score: 0.62Netrin-1 Gradient Restoration
Score: 0.59Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.90APOE-Dependent Autophagy Restoration
Score: 0.88Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
pg 1/2Next →

Related Analyses (22)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archivedEpigenetic reprogramming in aging neurons
neurodegeneration · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Related Experiments (4)

Ketamine in pediatric TRD patients
clinical · proposed · Score: 0.70Ketamine in obstetric TRD patients
clinical · proposed · Score: 0.70Ketamine efficacy in geriatric TRD patients
clinical · proposed · Score: 0.70Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40

See Also (10)

GABA (Gamma-Aminobutyric Acid) - Neurodegenerative Dise
biomarker · KG edge: inhibitsNeurodegeneration
disease · KG edge: co_discussedAmyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activatesglutamate
general · KG edge: activatesLong-Term Potentiation (LTP)
entity · KG edge: inhibits

Knowledge Graph (12 edges)

Memantine activates NMDA
Memantine inhibits NMDA
GLUTAMATE co_discussed NMDA
ALZHEIMER co_discussed NMDA
ALZHEIMER'S co_discussed NMDA
NEURODEGENERATION co_discussed NMDA
NEURONS co_discussed NMDA
AMYLOID activates NMDA
GENES co_discussed NMDA
NMDA activates P2Y12

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