gene 2,452 words KG: GRIN2A
Contents

GRIN2A Gene

🧬 Gene Info
Gene SymbolGRIN2A
AliasesNMDA Receptor Subunit 2A
Functionregulation implicated in Alzheimer's
Primary ExpressionPrefrontal Cortex, Cortex, Hippocampus
Molecular Weight180 kDa
Amino Acids838 aa
PathwaysNF-κB
GeneCardsGRIN2A
Human Protein AtlasGRIN2A
Associated DiseasesAlzheimer, schizophrenia
Known Drugs/CompoundsGW201
InteractionsActin, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, Amyloid Beta, APP
KG Connections170 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Astrocytes
cell · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activates
Astrocytes
entity · KG edge: activates
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: expressed_in

Knowledge Graph (12 edges)

GRIN2A co_discussed SNAP25
GRIN2A activates KCNIP4
GRIN2A co_discussed NCAM2
GRIN2A co_discussed NRXN1
GRIN2A co_discussed RORA
RORB activates GRIN2A
SLC17A7 biomarker_for GRIN2A
SLC17A6 biomarker_for GRIN2A
SLC12A5 biomarker_for GRIN2A
SYN2 biomarker_for GRIN2A

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