concept

ATP6V1G1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ATP6V1G1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections

0Hypotheses

0Analyses

35Outgoing

11Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ATP6V1G1
Key Genes/Proteins	Alpha-Synuclein, AND, Cathepsin, ENDOSOMES, EXOSOMES, Igf
Related Diseases	Als, ALS, Neurodegeneration

Pathway Diagram

graph TD
    ATP6V1G1["ATP6V1G1"]
    ATP6V1G1 -->|"expressed in"| V_ATPase["V-ATPase"]
    ATP6V1G1 -->|"activates"| Als["Als"]
    ATP6V1G1 -->|"activates"| ALS["ALS"]
    ATP6V1G1 -->|"target for"| Neurodegeneration["Neurodegeneration"]
    ATP6V1G1 -->|"target for"| Parkinson["Parkinson"]
    ATP6V1G1 -->|"target for"| Neuroinflammation["Neuroinflammation"]
    ATP6V1G1 -->|"activates"| ENDOSOMES["ENDOSOMES"]
    RILP["RILP"] -->|"interacts"| ATP6V1G1
    RAB7["RAB7"] -->|"activates"| ATP6V1G1
    RAB7A["RAB7A"] -->|"activates"| ATP6V1G1
    YAP["YAP"] -->|"activates"| ATP6V1G1
    AND["AND"] -->|"activates"| ATP6V1G1
    IGF2R["IGF2R"] -->|"activates"| ATP6V1G1
    ENDOSOMES -->|"activates"| ATP6V1G1

Outgoing (35)

Target	Relation	Type	Str
RAB7A	associated_with	protein	0.95
V-ATPase	associated_with	protein	0.90
V-ATPase	expressed_in	enzyme	0.85
lysosomal acidification	regulates	process	0.70
Parkinson's disease	associated_with	disease	0.70
Als	activates	disease	0.65
ALS	activates	disease	0.65
Als	causes	disease	0.65
Parkinson	therapeutic_target	disease	0.65
Neuroinflammation	therapeutic_target	disease	0.65
Als	associated_with	disease	0.65
Neurodegeneration	therapeutic_target	disease	0.65
PARKINSON	therapeutic_target	gene	0.60
NLR	associated_with	gene	0.60
Microglia	therapeutic_target	cell_type	0.60
Neuron	therapeutic_target	cell_type	0.60
Alpha-Synuclein	therapeutic_target	protein	0.60
Cathepsin	associated_with	protein	0.60
MICROGLIA	therapeutic_target	gene	0.60
Α-Synuclein	therapeutic_target	protein	0.60
LAMP1	associated_with	gene	0.60
LYSOSOME	therapeutic_target	gene	0.60
POLE	therapeutic_target	gene	0.60
RAB7	activates	gene	0.60
Raf	activates	protein	0.60
Igf	activates	protein	0.60
RILP	interacts_with	gene	0.60
ENDOSOMES	activates	gene	0.60
IGF2R	activates	gene	0.60
YAP	activates	gene	0.60
RAB7A	activates	gene	0.60
ENDOSOMES	causes	gene	0.60
YAP	causes	gene	0.60
IGF2R	causes	gene	0.60
RILP	activates	gene	0.60

Incoming (11)

Source	Relation	Type	Str
RILP	interacts_with	protein	0.85
PD-exo	inhibits	process	0.70
AND	activates	gene	0.60
RILP	activates	gene	0.60
RAB7	activates	gene	0.60
RAB7A	activates	gene	0.60
YAP	activates	gene	0.60
RAB7A	causes	gene	0.60
IGF2R	activates	gene	0.60
ENDOSOMES	activates	gene	0.60
EXOSOMES	targets	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ATP6V1G1 in their description or question text

No additional research found