Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MYO1C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MYO1C |
| Key Genes/Proteins | AXIN1, CCND1, CEBPA, EGR1, FOXO3, HNF4A |
| Related Diseases | obesity |
graph TD
MYO1C[MYO1C]
MYO1C -->|regulates| chromatin_accessibility[chromatin accessibility]
MYO1C -->|regulates| adipocyte_differentiation[adipocyte differentiation]
MYO1C -->|upregulates| CEBPA[CEBPA]
MYO1C -->|upregulates| PLIN2[PLIN2]
MYO1C -.protects against.-> obesity[obesity]
MYO1C -->|regulates| KLF6[KLF6]
MYO1C -->|regulates| FOXO3[FOXO3]
MYO1C -->|regulates| Adipose_Tissue_Remodeling[Adipose Tissue Remodeling]
MYO1C -->|activates| RELA[RELA]
MYO1C -->|activates| RHEB[RHEB]
AXIN1[AXIN1] -->|activates| MYO1C
EGR1[EGR1] -->|activates| MYO1C
HNF4A[HNF4A] -->|activates| MYO1C
MYC[MYC] -->|activates| MYO1C
CCND1[CCND1] -->|activates| MYO1C
MYH9[MYH9] -->|activates| MYO1C
benchmark_ot_ad_answer_key_MYO[benchmark_ot_ad_answer_key:MYO1C] -->|data_in| MYO1C| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:MYO1C | data_in | dataset_row | 0.00 |
| chromatin accessibility | regulates | process | 0.95 |
| adipocyte differentiation | regulates | process | 0.90 |
| metabolic homeostasis | associated_with | process | 0.90 |
| obesity | protects_against | disease | 0.85 |
| CEBPA | upregulates | gene | 0.85 |
| PLIN2 | upregulates | gene | 0.85 |
| FOXO3 | regulates | gene | 0.80 |
| KLF6 | regulates | gene | 0.80 |
| Adipose Tissue Remodeling | regulates | process | 0.80 |
| oxidative stress response | participates_in | pathway | 0.60 |
| RELA | activates | gene | 0.60 |
| RHEB | activates | gene | 0.60 |
| SOCS3 | activates | gene | 0.60 |
| SPI1 | activates | gene | 0.60 |
| STAT3 | activates | gene | 0.60 |
| TBP | activates | gene | 0.60 |
| TXNIP | activates | gene | 0.60 |
| YWHAZ | activates | gene | 0.60 |
| RHEB | regulates | gene | 0.60 |
| SOCS3 | regulates | gene | 0.60 |
| TF | regulates | gene | 0.60 |
| TXNIP | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MYO1C in their description or question text
No additional research found