concept

LGALS8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LGALS8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections

0Hypotheses

0Analyses

32Outgoing

14Incoming

0Experiments

0Debates

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💡 Concept Info

Name	LGALS8
Key Genes/Proteins	Actin, AND, App, ATF4, ATG, ATG8
Related Diseases	Aging, Als, ALS, Cancer
Related Pathways	Autophagy, Er Stress

Pathway Diagram

graph TD
    LGALS8["LGALS8"]
    LGALS8 -->|"inhibits"| MTOR["MTOR"]
    LGALS8 -->|"encodes"| galectin_8["galectin-8"]
    LGALS8 -->|"interacts"| Aging["Aging"]
    LGALS8 -->|"interacts"| ALS["ALS"]
    LGALS8 -->|"interacts"| Cancer["Cancer"]
    LGALS8 -->|"interacts"| Als["Als"]
    LGALS8 -->|"interacts"| AUTOPHAGY["AUTOPHAGY"]
    G3BP1["G3BP1"] -->|"interacts"| LGALS8
    ATG8["ATG8"] -->|"interacts"| LGALS8
    EIF2A["EIF2A"] -->|"interacts"| LGALS8
    GABARAP["GABARAP"] -->|"interacts"| LGALS8
    FMR1["FMR1"] -->|"interacts"| LGALS8
    LYSOSOME["LYSOSOME"] -->|"interacts"| LGALS8
    RNA["RNA"] -->|"interacts"| LGALS8
    ATF4["ATF4"] -->|"interacts"| LGALS8

Outgoing (32)

Target	Relation	Type	Str
MTOR	inhibits	entity	0.90
galectin-8	encodes	protein	0.70
Cancer	interacts_with	disease	0.65
Als	interacts_with	disease	0.65
Aging	interacts_with	disease	0.65
ALS	interacts_with	disease	0.65
NUFIP2	interacts_with	gene	0.60
MTOR	interacts_with	gene	0.60
AUTOPHAGY	interacts_with	gene	0.60
MAPT	interacts_with	gene	0.60
JUN	interacts_with	gene	0.60
GABARAP	interacts_with	gene	0.60
ATF4	interacts_with	gene	0.60
LYSOSOME	interacts_with	gene	0.60
RRAGA	interacts_with	gene	0.60
RRAGB	interacts_with	gene	0.60
EIF2A	interacts_with	gene	0.60
CANCER	interacts_with	gene	0.60
ATG	interacts_with	gene	0.60
FMR1	interacts_with	gene	0.60
TIA1	interacts_with	gene	0.60
TAU	interacts_with	gene	0.60
Er Stress	interacts_with	pathway	0.60
Mtor	interacts_with	pathway	0.60
Autophagy	interacts_with	pathway	0.60
G3BP1	interacts_with	gene	0.60
ATG8	interacts_with	gene	0.60
AND	interacts_with	gene	0.60
GABA	interacts_with	gene	0.60
RNA	interacts_with	gene	0.60
Actin	interacts_with	protein	0.60
App	interacts_with	protein	0.60

Incoming (14)

Source	Relation	Type	Str
TIA1	interacts_with	gene	0.60
AUTOPHAGY	interacts_with	gene	0.60
EIF2A	interacts_with	gene	0.60
GABARAP	interacts_with	gene	0.60
FMR1	interacts_with	gene	0.60
LYSOSOME	interacts_with	gene	0.60
RNA	interacts_with	gene	0.60
ATF4	interacts_with	gene	0.60
ATG	interacts_with	gene	0.60
JUN	interacts_with	gene	0.60
MTOR	interacts_with	gene	0.60
GABA	interacts_with	gene	0.60
G3BP1	interacts_with	gene	0.60
ATG8	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning LGALS8 in their description or question text

No additional research found