concept

NUFIP2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NUFIP2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

27Connections

0Hypotheses

0Analyses

10Outgoing

17Incoming

0Experiments

0Debates

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💡 Concept Info

Name	NUFIP2
Key Genes/Proteins	ATF4, ATG, EIF2A, FMR1, G3BP1, GABA
Related Pathways	autophagy pathway

Pathway Diagram

graph TD
    NUFIP2[NUFIP2]
    NUFIP2 -->|inhibits| MTOR[MTOR]
    NUFIP2 -->|interacts| TDP_43[TDP-43]
    NUFIP2 -->|contributes to| TDP_43_Aggregation[TDP-43 Aggregation]
    NUFIP2 -->|interacts| RRAGA[RRAGA]
    NUFIP2 -->|interacts| RRAGB[RRAGB]
    NUFIP2 -->|activates| TIA1[TIA1]
    NUFIP2 -->|activates| SARS[SARS]
    NUFIP2 -->|participates in| autophagy_pathway[autophagy pathway]
    NUFIP2 -->|activates| RNA[RNA]
    NUFIP2 -->|data_in| benchmark_ot_ad_answer_key_NUF[benchmark_ot_ad_answer_key:NUFIP2]
    GABARAP[GABARAP] -->|interacts| NUFIP2
    G3BP1[G3BP1] -->|interacts| NUFIP2
    MTOR -->|interacts| NUFIP2
    ATF4[ATF4] -->|activates| NUFIP2
    EIF2A[EIF2A] -->|activates| NUFIP2
    FMR1[FMR1] -->|activates| NUFIP2

Outgoing (10)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:NUFIP2	data_in	dataset_row	0.00
MTOR	inhibits	entity	0.90
TDP-43	interacts_with	protein	0.85
TDP-43 Aggregation	contributes_to	phenotype	0.80
RNA	activates	gene	0.60
autophagy pathway	participates_in	pathway	0.60
SARS	activates	gene	0.60
RRAGA	interacts_with	gene	0.60
RRAGB	interacts_with	gene	0.60
TIA1	activates	gene	0.60

Incoming (17)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:NUFIP2	data_in	dataset_row	0.00
GABARAP	interacts_with	protein	0.90
LGALS8	interacts_with	gene	0.60
ATG	activates	gene	0.60
GABA	activates	gene	0.60
rapamycin	targets	drug	0.60
G3BP1	interacts_with	gene	0.60
MTOR	interacts_with	gene	0.60
G3BP1	regulates	gene	0.60
GABARAP	regulates	gene	0.60
MTOR	regulates	gene	0.60
ATF4	activates	gene	0.60
EIF2A	activates	gene	0.60
FMR1	activates	gene	0.60
G3BP1	activates	gene	0.60
GABARAP	activates	gene	0.60
MTOR	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NUFIP2 in their description or question text

No additional research found