concept

IL12

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL12: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

43Connections

0Hypotheses

0Analyses

30Outgoing

13Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	IL12
Key Genes/Proteins	AND, AVP, C5, CRH, CRHR1, Cytokine
Related Diseases	Alopecia Areata, Als, ALS
Related Pathways	Er Stress

Wiki Pages (2)

Knowledge base pages for this entity

IL12A — Interleukin-12 Alpha

gene · 1066 words

→

IL12B Gene - Interleukin 12 Beta

gene · 695 words

→

Pathway Diagram

graph TD
    IL12["IL12"]
    IL12 -->|"component_of"| IL35["IL35"]
    IL12 -->|"involved_in"| Alopecia_Areata["Alopecia Areata"]
    IL12 -->|"expressed in"| Tumor["Tumor"]
    IL12 -->|"activates"| ALS["ALS"]
    IL12 -->|"activates"| Als["Als"]
    IL12 -->|"expressed in"| ESR2["ESR2"]
    IL12 -->|"expressed in"| NR3C2["NR3C2"]
    IL12 -->|"expressed in"| TNF["TNF"]
    AVP["AVP"] -->|"expressed in"| IL12
    ESR1["ESR1"] -->|"expressed in"| IL12
    CRH["CRH"] -->|"expressed in"| IL12
    NR3C1["NR3C1"] -->|"expressed in"| IL12
    CRHR1["CRHR1"] -->|"expressed in"| IL12
    POMC["POMC"] -->|"expressed in"| IL12
    TNF -->|"expressed in"| IL12
    ESR2 -->|"expressed in"| IL12

Outgoing (30)

Target	Relation	Type	Str
IL35	component_of	protein	0.90
Alopecia Areata	associated_with	disease	0.80
IL30	associated_with	gene	0.80
FOXP3(lo) non-Treg cells	promotes	cell_type	0.75
Tumor	expressed_in	disease	0.65
Als	activates	disease	0.65
ALS	activates	disease	0.65
oxidative stress response	participates_in	pathway	0.60
Immune Response	activates	pathway	0.60
Er Stress	activates	pathway	0.60
TNF	associated_with	gene	0.60
Interleukin	expressed_in	protein	0.60
Cytokine	activates	protein	0.60
IL18	associated_with	gene	0.60
IL4	associated_with	gene	0.60
IL6	associated_with	gene	0.60
NR3C2	expressed_in	gene	0.60
TNF	expressed_in	gene	0.60
CYTOKINES	activates	gene	0.60
CRHR1	expressed_in	gene	0.60
CRH	expressed_in	gene	0.60
POMC	expressed_in	gene	0.60
ESR2	expressed_in	gene	0.60
NR3C1	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
AVP	expressed_in	gene	0.60
ESR1	expressed_in	gene	0.60
Raf	activates	protein	0.60
Rb	activates	protein	0.60
JUN	activates	gene	0.60

Incoming (13)

Source	Relation	Type	Str
AVP	expressed_in	gene	0.60
ESR1	expressed_in	gene	0.60
CRH	expressed_in	gene	0.60
NR3C1	expressed_in	gene	0.60
CRHR1	expressed_in	gene	0.60
POMC	expressed_in	gene	0.60
TNF	expressed_in	gene	0.60
ESR2	expressed_in	gene	0.60
JUN	activates	gene	0.60
NR3C2	expressed_in	gene	0.60
CYTOKINES	activates	gene	0.60
C5	associated_with	gene	0.60
IL10	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning IL12 in their description or question text

No additional research found