gene

CCT4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CCT4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

67Connections

0Hypotheses

0Analyses

40Outgoing

27Incoming

0Experiments

0Debates

No summary available yet.

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🧬 Gene Info

Gene Symbol	CCT4
Full Name	Chaperonin Containing TCP1 Subunit 4 (Delta)
Chromosome	2p15
Protein Type	Chaperone
Molecular Weight	58 kDa
Amino Acids	539 aa
Exons	12
UniProt ID	P50991
NCBI Gene ID	10382
Ensembl ID	ENSG00000108771
OMIM	605588
GeneCards	CCT4
Human Protein Atlas	CCT4
Associated Diseases	Als, Alzheimer
Interactions	ALZHEIMER, APOE, APP, CALB1, COPA, IDS
KG Connections	67 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CCT4 — AlphaFold P50991 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

cct4

gene · 1101 words

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Pathway Diagram

graph TD
    CCT4["CCT4"]
    Alzheimer["Alzheimer"]
    Als["Als"]
    CALB1["CALB1"]
    SORL1["SORL1"]
    IGF2R["IGF2R"]
    COPA["COPA"]
    STXBP3["STXBP3"]
    RNF14["RNF14"]
    IDS["IDS"]
    SYNCRIP["SYNCRIP"]
    SSBP1["SSBP1"]
    PRDX3["PRDX3"]
    APP["APP"]
    ALZHEIMER["ALZHEIMER"]
    APOE["APOE"]
    SYNE2["SYNE2"]
    SMARCB1["SMARCB1"]
    ULK2["ULK2"]
    TMEM59["TMEM59"]
    SFPQ["SFPQ"]
    CCT4 -.-|"associated"| Alzheimer
    CCT4 -.-|"associated"| Als
    CCT4 -.-|"associated"| CALB1
    CCT4 -.-|"associated"| SORL1
    CCT4 -.-|"associated"| IGF2R
    CCT4 -.-|"associated"| COPA
    CCT4 -.-|"associated"| STXBP3
    CCT4 -.-|"associated"| RNF14
    IDS -.-|"associated"| CCT4
    SYNCRIP -.-|"associated"| CCT4
    SSBP1 -.-|"associated"| CCT4
    PRDX3 -.-|"associated"| CCT4
    APP -.-|"associated"| CCT4
    ALZHEIMER -.-|"associated"| CCT4
    APOE -.-|"associated"| CCT4
    SYNE2 -.-|"associated"| CCT4
    SMARCB1 -.-|"associated"| CCT4
    ULK2 -.-|"associated"| CCT4
    TMEM59 -.-|"associated"| CCT4
    SFPQ -.-|"associated"| CCT4
    style CCT4 fill:#006494,stroke:#333,color:#e0e0e0,stroke-width:2px

Outgoing (40)

Target	Relation	Type	Str
ALS	associated_with	disease	0.65
Als	associated_with	disease	0.65
Alzheimer	associated_with	disease	0.65
STXBP3	associated_with	gene	0.60
RNF14	associated_with	gene	0.60
SFPQ	associated_with	gene	0.60
SMARCB1	associated_with	gene	0.60
SYNE2	associated_with	gene	0.60
CALB1	associated_with	gene	0.60
SORL1	associated_with	gene	0.60
IGF2R	associated_with	gene	0.60
AND	associated_with	gene	0.60
GENES	associated_with	gene	0.60
ALZHEIMER	associated_with	gene	0.60
Igf	associated_with	protein	0.60
App	associated_with	protein	0.60
Alzheimer's disease	interacts_with	disease	0.60
PRDX3	associated_with	gene	0.60
COPA	associated_with	gene	0.60
TMEM59	associated_with	gene	0.60
SYNCRIP	associated_with	gene	0.60
IDS	associated_with	gene	0.60
ULK2	associated_with	gene	0.60
SSBP1	associated_with	gene	0.60
IDS	interacts_with	gene	0.60
PRDX3	interacts_with	gene	0.60
RNF14	interacts_with	gene	0.60
SMARCB1	interacts_with	gene	0.60
SSBP1	interacts_with	gene	0.60
SYNE2	interacts_with	gene	0.60
TMEM59	interacts_with	gene	0.60
SFPQ	interacts_with	protein	0.50
IGF2R	interacts_with	protein	0.50
SYNCRIP	interacts_with	concept	0.50
STXBP3	interacts_with	gene	0.50
ULK2	interacts_with	gene	0.50
SORL1	interacts_with	gene	0.50
COPA	interacts_with	protein	0.50
ALZHEIMER	interacts_with	gene	0.50
ALZHEIMER'S	interacts_with	concept	0.50

Incoming (27)

Source	Relation	Type	Str
IDS	associated_with	gene	0.60
SYNCRIP	associated_with	gene	0.60
SSBP1	associated_with	gene	0.60
PRDX3	associated_with	gene	0.60
APP	associated_with	gene	0.60
APOE	associated_with	gene	0.60
SYNE2	associated_with	gene	0.60
SMARCB1	associated_with	gene	0.60
ULK2	associated_with	gene	0.60
TMEM59	associated_with	gene	0.60
SFPQ	associated_with	gene	0.60
RNF14	associated_with	gene	0.60
STXBP3	associated_with	gene	0.60
IGF2R	associated_with	gene	0.60
SORL1	associated_with	gene	0.60
COPA	associated_with	gene	0.60
CALB1	associated_with	gene	0.60
APP	interacts_with	gene	0.60
ALZHEIMER	associated_with	gene	0.60
SYNE2	interacts_with	gene	0.50
SMARCB1	interacts_with	gene	0.50
TMEM59	interacts_with	gene	0.50
APOE	interacts_with	gene	0.50
SSBP1	interacts_with	gene	0.50
CALB1	interacts_with	gene	0.50
RNF14	interacts_with	gene	0.50
PRDX3	interacts_with	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CCT4 in their description or question text

No additional research found