Contents

POLD1 Protein

🔬 Protein Info

Gene Symbol	POLD1
Chromosome	19q13.3
Protein Family	DNA polymerase delta family
Function	The enzyme exhibits lower processivity compared to Pol ε (the leading strand polymerase) but achieves high fidelity through its intrinsic 3'→5' exonuclease proofreading activity[@burgers2019].
Subcellular Localization	Nucleus
Molecular Weight	124 kDa
UniProt ID	[P28340](https://www.uniprot.org/uniprot/P28340)
GeneCards	POLD1
Human Protein Atlas	POLD1
Associated Diseases	neurodegeneration
Interactions	ATM, MRE11, MUTYH, NBS1, NEIL1, P53
KG Connections	18 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

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