| Gene Symbol | NESTIN |
| Chromosome | 1q23.1 |
| Protein Family | Class VI intermediate filaments |
| Function | is a protein encoded by the NES gene. |
| Primary Expression | neural stem and progenitor cells during development and in adult neurogenic regions[@reynolds1992]: |
| Subcellular Localization | Cytoplasm, intermediate filaments |
| Molecular Weight | 220 kDa |
| Amino Acids | 4477 aa |
| Pathways | Circadian Rhythm, Mapk, Mitochondrial Function, Wnt |
| UniProt ID | P48681 |
| NCBI Gene ID | 4756 |
| Ensembl ID | ENSG00000132688 |
| GeneCards | NESTIN |
| Human Protein Atlas | NESTIN |
| Neurogenesis | Serves as a structural scaffold for neural progenitor cells during proliferation and differentiation[@wiese2004] |
| Associated Diseases | Neurodevelopmental disorders, Brain tumors, Alzheimer's disease, Parkinson's disease, Stroke |
| Interactions | AKT, ALDH1L1, ALZHEIMER, ALZHEIMER'S DISEASE, AND, ARC |
| KG Connections | 164 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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