| Gene Symbol | CASP3 |
| Full Name | Caspase-3 (CASP3) |
| Aliases | CASPASE3 |
| Chromosome | 4q35.1. |
| Protein Family | Cysteine-aspartate protease (caspase) family |
| Protein Type | Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Cytoplasm, mitochondria (activated) |
| Molecular Weight | 32 kDa (zymogen); 17 + 12 kDa (active heterodimer) |
| Pathways | Apoptosis |
| UniProt ID | P42574 |
| GeneCards | CASP3 |
| Human Protein Atlas | CASP3 |
| Structural Proteins | Lamin A/C, actin, tubulin |
| DNA Repair Enzymes | PARP (poly ADP-ribose polymerase) |
| Associated Diseases | Lymphoma |
| Interactions | AGING, AKT, AKT1, ALZHEIMER, ALZHEIMER'S DISEASE, AND |
| KG Connections | 220 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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