protein 1,419 words KG: BECLIN1
Contents

Beclin-1

🔬 Protein Info
Gene SymbolBECLIN1
Full NameBECN1
Chromosome17q21
Protein TypeGene
Functionis a gene/protein encoding a key neuronal protein involved in synaptic function, signal transduction, and cellular homeostasis
PathwaysApoptosis, Autophagy, Mtor, Oxidative Stress
GeneCardsBECLIN1
Human Protein AtlasBECLIN1
Associated DiseasesAls, Alzheimer, Cancer, Colorectal Cancer, Glioblastoma, Inflammation
InteractionsABCA1, ACTB, ADSL, AKT, AKT1, ALZHEIMER
KG Connections618 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (22)

Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
← Prevpg 2/2

Related Analyses (6)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (3)

CLOCK/BMAL1 regulation of ICC autophagy in GERD model
exploratory · proposed · Score: 0.90
Autophagy Enhancement Drug Screening for Neurodegeneration
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (8)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: inhibits
ACTB Gene
gene · KG edge: activates
AKT1 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

CHOP regulates BECLIN1
FIS1 associated_with BECLIN1
VEGF associated_with BECLIN1
BAX associated_with BECLIN1
TRAF6 associated_with BECLIN1
CHOP associated_with BECLIN1
NRF2 associated_with BECLIN1
MTOR associated_with BECLIN1
BECLIN1 associated_with BCL2
BECLIN1 associated_with TAAR1

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