| Gene Symbol | APEX2 |
| Full Name | Apurinic/Apyrimidinic Endodeoxyribonuclease 2 |
| Chromosome | 11p13 |
| Protein Type | Enzyme |
| Function | encodes a DNA repair enzyme that plays a critical role in the base excision repair (BER) pathway. |
| Primary Expression | various brain regions with both nuclear and mitochondrial localization: |
| Molecular Weight | 57 kDa |
| Amino Acids | 513 aa |
| UniProt ID | Q9GZL2 |
| NCBI Gene ID | 27351 |
| Ensembl ID | ENSG00000164073 |
| OMIM | 607538 |
| GeneCards | APEX2 |
| Human Protein Atlas | APEX2 |
| DNA binding domain | Recognizes AP sites in DNA |
| Associated Diseases | neurodegeneration |
| Interactions | AMPK, AUTOPHAGY, RNA, TAK1, UBIQUITIN |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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