| Gene Symbol | TNFSF10 |
| Full Name | TNF Superfamily Member 10 (TNF-Related Apoptosis-Inducing Ligand) |
| Chromosome | 3q26.1 |
| Protein Family | TNF superfamily, Type II transmembrane proteins |
| Function | is a member of the tumor necrosis factor (TNF) superfamily that plays complex roles in cell death, immune surveillance, and neuroinflammation. |
| Amino Acids | 281 aa |
| Pathways | Apoptosis, Immune Response |
| UniProt ID | [P50591](https://www.uniprot.org/uniprot/P50591) |
| Ensembl ID | ENSG00000117586 |
| GeneCards | TNFSF10 |
| Human Protein Atlas | TNFSF10 |
| TRAIL-α | Full-length membrane-bound form |
| TRAIL-β | Soluble form generated by proteolytic cleavage |
| TRAIL-γ | Truncated variant with altered signaling |
| Associated Diseases | Als, Cancer, Carcinoma, Ms, Tumor |
| Interactions | AND, APAF1, APOPTOSIS, CALR, CANCER, CANX |
| KG Connections | 45 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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