gene 611 words KG: TNFRSF1A
Contents

TNFRSF1A Gene

🧬 Gene Info
Gene SymbolTNFRSF1A
Full NameTumor necrosis factor receptor superfamily member 1A
AliasesTNFR1
Chromosome12p13.31
FunctionTNFRSF1A encodes TNFR1, a receptor that plays central roles in inflammation and cell survival:
Molecular Weight55 kDa
Amino Acids455 aa
Exons10
PathwaysNF-κB Signaling, NF-κB, MAPK Pathway, MAPK
UniProt IDP19438
NCBI Gene ID7132
Ensembl IDENSG00000082258
OMIM191190
GeneCardsTNFRSF1A
Human Protein AtlasTNFRSF1A
Associated DiseasesAtherosclerosis, Diabetes, Ms
InteractionsANXIETY, APOPTOSIS, App, ARNT, BMAL1, CANCER
KG Connections153 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Blood-Brain Barrier SPM Shuttle System
Score: 0.53

Related Analyses (5)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Apoptosis in Neurodegeneration
entity · KG edge: regulates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
AKT1 Gene
gene · KG edge: biomarker_for
ARNT - Aryl Hydrocarbon Receptor Nuclear Translocator
gene · KG edge: activates
BCL2L1 Gene
gene · KG edge: biomarker_for

Knowledge Graph (12 edges)

CRY1 activates TNFRSF1A
BMAL1 activates TNFRSF1A
ARNT activates TNFRSF1A
TNF activates TNFRSF1A
TNFRSF1A activates OCLN
TNFRSF1A activates ICAM1
OCLN activates TNFRSF1A
TNFRSF1A activates BMAL1
TNFRSF1A activates ARNT
ARNT contributes_to TNFRSF1A

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