gene 3,796 words KG: FGF10
Contents

FGF10 — Fibroblast Growth Factor 10

🧬 Gene Info
Gene SymbolFGF10
Full NameFibroblast Growth Factor 10
Chromosome5p12
Functionencodes a critical member of the fibroblast growth factor family that plays essential roles in embryonic development, tissue morphogenesis, and cellular proliferation.
Primary Expressionepithelial and neuronal tissues[@kumar1998]
Molecular Weight23.4 kDa
Amino Acids208 aa
UniProt IDO15520
NCBI Gene ID2255
Ensembl IDENSG00000164283
OMIM602115
GeneCardsFGF10
Human Protein AtlasFGF10
N-terminal signal peptideDirects secretion
FGF core domainConserved 120-amino acid core
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsAPOPTOSIS, CANCER, CD44, CDKN2A, COL4A1, CYTOKINES
KG Connections38 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (5)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67

Related Analyses (3)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (6)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Blood Biomarker vs Tau PET for Treatment Monitoring
clinical · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40
Microbiome-Gut-Brain Axis in Alzheimer's Disease — mechanism
clinical · proposed · Score: 0.40

See Also (13)

Apoptosis in Neurodegeneration
entity · KG edge: inhibits
CD44 - Cell Surface Glycoprotein
gene · KG edge: inhibits
cdkn2a
gene · KG edge: inhibits
COL4A1 Gene
gene · KG edge: inhibits
DCC
gene · KG edge: inhibits

Knowledge Graph (12 edges)

CDKN2A inhibits FGF10
TLR4 inhibits FGF10
TNC inhibits FGF10
NTRK2 inhibits FGF10
PAK1 inhibits FGF10
WNT7A inhibits FGF10
LZTS1 inhibits FGF10
DCC inhibits FGF10
KCNK2 inhibits FGF10
CD44 inhibits FGF10

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