Contents

SPI1 Gene - PU.1

🧬 Gene Info

Gene Symbol	SPI1
Full Name	PU.1 Transcription Factor / Spi-1 Proto-Oncogene
Aliases	SPI1/PU.1
Chromosome	19q13.3
Protein Type	Transcription Factor
Function	encodes a transcription factor of the E26 transformation-specific (ETS) family.
Amino Acids	270 aa
Pathways	Amyloid, Mtor, Pi3K/Akt
UniProt ID	P17947
NCBI Gene ID	6678
Ensembl ID	ENSG00000135336
OMIM	165010
GeneCards	SPI1
Human Protein Atlas	SPI1
Associated Diseases	AD, ALI, Als, Alzheimer, Alzheimer's disease
Interactions	Actin, AKT, ALZHEIMER, ALZHEIMER DISEASE, ALZHEIMER'S DISEASE, AMYLOID
KG Connections	427 knowledge graph edges
Databases	GeneCards HPA STRING

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Knowledge Graph

GBM associated_with SPI1

C1Q expressed_in SPI1

C1QA expressed_in SPI1

C1QC expressed_in SPI1

SPI1 associated_with APOE

CEBPA regulates SPI1

HSPA1A therapeutic_target SPI1

TFE3 regulates SPI1

TP53 regulates SPI1

SPI1 expressed_in C1QA