gene 2,041 words KG: ABI3
Contents

ABI3 Gene

🧬 Gene Info
Gene SymbolABI3
Full NameABI Family Member 3 (Abl Interactor 3)
AliasesAbl Interactor 3, ABI3 protein
Chromosome17q21.31
Functionis a gene located on chromosome 17q21.
Molecular Weight52 kDa
Amino Acids360 aa
UniProt IDQ9NZU7
NCBI Gene ID10027
Ensembl IDENSG00000108506
OMIM609469
GeneCardsABI3
Human Protein AtlasABI3
Associated DiseasesALZHEIMER'S DISEASE, DEMENTIA
InteractionsActin, ALZHEIMER, ALZHEIMER DISEASE, AMYLOID, COMPLEMENT, LRP1
KG Connections109 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (20)

APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
APOE Isoform Conversion Therapy
Score: 0.72
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79

Related Analyses (6)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (15)

Actin Cytoskeleton Dynamics in Neurodegeneration
mechanism · KG edge: activates
ABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: associated_with
ACE Gene
gene · KG edge: associated_with
adam17
gene · KG edge: associated_with
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_with

Knowledge Graph (12 edges)

ABI3 regulates TREM2
ABI3 regulates PLCG2
NBR1 regulates ABI3
CTSH associated_with ABI3
PTK2B associated_with ABI3
CD2AP associated_with ABI3
APOE associated_with ABI3
CR1 associated_with ABI3
BIN1 associated_with ABI3
LILRB2 associated_with ABI3

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