| Gene Symbol | SESN2 |
| Full Name | Sestrin 2 |
| Chromosome | 1p35.3 |
| Protein Family | Sestrin family (SESN1-3) |
| Function | is a stress-inducible protein that functions as a critical regulator of cellular homeostasis, metabolic adaptation, and stress resistance [1]. |
| Molecular Weight | 57 kDa |
| Amino Acids | 504 aa |
| Pathways | signaling: ```mermaid, mTOR, mtor, AMPK, AMPK signaling |
| UniProt ID | Q9Y7X7 |
| NCBI Gene ID | 83667 |
| Ensembl ID | ENSG00000140299 |
| OMIM | 607336 |
| GeneCards | SESN2 |
| Human Protein Atlas | SESN2 |
| N-terminal domain (1-170) | Leucine-rich repeat (LRR) motif for protein-protein interactions |
| Associated Diseases | AD, ALI, Als, Alzheimer, Alzheimer's disease |
| Interactions | ABCD3, Actin, ALS, ALZHEIMER, ALZHEIMER DISEASE, AMBRA1 |
| KG Connections | 549 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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