gene 561 words KG: SDHB
Contents

SDHB Gene

🧬 Gene Info
Gene SymbolSDHB
FunctionThe SDHB gene encodes SDHB Protein, a protein involved in various cellular processes relevant to neuronal function and survival.
Primary Expressionvarious brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang
PathwaysDna Methylation, Complement
Ensembl IDENSG00000117118
GeneCardsSDHB
Human Protein AtlasSDHB
Associated DiseasesALS, Kidney Cancer
InteractionsACETYL-COA, AGING, AMPK, ATP5F1, BACE1, C-FOS
KG Connections41 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (12)

Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Circadian Clock-Autophagy Synchronization
Score: 0.76
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.73
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Autophagosome Maturation Checkpoint Control
Score: 0.71
Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Temporal Decoupling via Circadian Clock Reset
Score: 0.54

Related Analyses (11)

Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived

See Also (15)

Parkinson Basal Ganglia Circuit
circuit · KG edge: interacts_with
Neurodegeneration
disease · KG edge: implicated_in
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: interacts_with
BACE1 (Redirect)
redirect · KG edge: interacts_with
DNA Methylation
entity · KG edge: associated_with

Knowledge Graph (12 edges)

STX17 associated_with SDHB
ATP5MC1 regulates SDHB
TXNRD1 regulates SDHB
MFN2 regulates SDHB
UNG associated_with SDHB
SIRT3 interacts_with SDHB
PGC1A interacts_with SDHB
ATP5F1 interacts_with SDHB
LMNA interacts_with SDHB
CLOCK interacts_with SDHB

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