| Gene Symbol | MFN2 |
| Aliases | Mitofusin 2 |
| Chromosome | 1p36.22 |
| Function | Trans-tethering: HR2 domains form antiparallel complexes between adjacent mitochondria |
| Molecular Weight | 84 kDa |
| Amino Acids | 757 aa |
| Exons | 17 |
| Pathways | NF-κB, AMPK |
| GeneCards | MFN2 |
| Human Protein Atlas | MFN2 |
| PPARγ response elements | Enabling regulation by peroxisome proliferator-activated receptor gamma |
| FoxO1 binding sites | Allowing forkhead transcription factor regulation |
| NF-κB sites | Mediating inflammatory responses |
| AMPK-responsive elements | Enabling metabolic regulation |
| Associated Diseases | aging, Als, CHARCOT-MARIE-TOOTH, Charcot-Marie-Tooth Type 2A, Fibrosis, Hereditary Polyneuropathy |
| Known Drugs/Compounds | 8015-P2, Piperine |
| Interactions | ABCG2, AGING, AKT, AKT1, ALZHEIMER, ALZHEIMER'S DISEASE |
| KG Connections | 720 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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