gene 587 words KG: TXNRD1
Contents

TXNRD1 — Thioredoxin Reductase 1

🧬 Gene Info
Gene SymbolTXNRD1
Full NameThioredoxin Reductase 1
Chromosome12q23.3
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
Amino Acids500 aa
PathwaysDna Methylation
UniProt IDQ16881
NCBI Gene ID7296
Ensembl IDENSG00000198431
GeneCardsTXNRD1
Human Protein AtlasTXNRD1
Associated DiseasesALS, Alzheimer, depression, Inflammation, Macular Degeneration
InteractionsAKT, APOPTOSIS, APP, AUTOPHAGY, , Bdnf
KG Connections126 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (5)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Autophagosome Maturation Checkpoint Control
Score: 0.71
Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration
Score: 0.70

Related Analyses (3)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Microglial Aging and Immune Memory in Neurodegeneration — Tr
validation · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40
Sirtuin Pathway Dysfunction Validation in Parkinson's Diseas
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: activates
NGF (Redirect)
redirect · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: causes
nad-augmentation-therapy-early-ad
general · KG edge: activates
Genes
index · KG edge: biomarker_for

Knowledge Graph (12 edges)

NRF2 regulates TXNRD1
NQO1 regulates TXNRD1
HMOX1 regulates TXNRD1
TXNRD1 regulates NRF2
TXNRD1 regulates GCLM
TXNRD1 regulates GCLC
GCLC regulates TXNRD1
GCLM regulates TXNRD1
STX17 associated_with TXNRD1
ATP5MC1 regulates TXNRD1

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