Contents

PGC1A Gene

🧬 Gene Info

Gene Symbol	PGC1A
Full Name	PPARG Coactivator 1 Alpha
Chromosome	4p15.1
Target Class	Protein
Function	is an important component in the neurobiology of neurodegenerative diseases.
Mechanism of Action	Prioritized from 1 SciDEX hypotheses, including: Metabolic Reprogramming via Coordinated Multi-Gene CRISPR Circuits
Primary Expression	neurons, astrocytes, and oligodendrocytes [18] - Regulation: Highly responsive to environmental and h
Druggability	Undruggable (0.23)
Molecular Weight	91 kDa
Pathways	AMPK, MAPK pathway
UniProt ID	Q9UBX3
NCBI Gene ID	10887
Ensembl ID	ENSG00000100739
GeneCards	PGC1A
Human Protein Atlas	PGC1A
Associated Diseases	Aging, Als, Breast Cancer, Cancer, Huntington's disease, neurodegeneration
Interactions	ACETYL-COA, AGING, AMPK, AND, APOE, ATP
SciDEX Target	View Target Profile
KG Connections	202 knowledge graph edges
Databases	GeneCards HPA STRING