gene 4,040 words KG: ATP5F1
Contents

ATP5F1 — ATP Synthase F1 Subunit Beta

🧬 Gene Info
Gene SymbolATP5F1
Full NameATP Synthase F1 Subunit Beta
Chromosome1p13.3
Functionencodes the beta subunit of the F1 catalytic sector of mitochondrial ATP synthase, also known as Complex V of the electron transport chain[@nature2010]
Primary ExpressionBrain, Heart, Muscle
Amino Acids511 aa
UniProt IDP06576
NCBI Gene ID547
Ensembl IDENSG00000067715
GeneCardsATP5F1
Human Protein AtlasATP5F1
InteractionsACETYL-COA, AGING, AMPK, BACE1, CLOCK, HUNTINGTON'S DISEASE
KG Connections20 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Circadian Clock-Autophagy Synchronization
Score: 0.76
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration
Score: 0.70
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Temporal Decoupling via Circadian Clock Reset
Score: 0.54

Related Analyses (3)

Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived

Related Experiments (1)

Synaptic Mitochondrial Resilience Enhancement for Parkinson'
validation · proposed · Score: 0.40

See Also (15)

Parkinson Basal Ganglia Circuit
circuit · KG edge: interacts_with
Neurodegeneration
disease · KG edge: implicated_in
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: interacts_with
BACE1 (Redirect)
redirect · KG edge: interacts_with
CLOCK Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

SIRT3 interacts_with ATP5F1
PGC1A interacts_with ATP5F1
ATP5F1 interacts_with LMNA
ATP5F1 interacts_with CLOCK
ATP5F1 interacts_with SDHB
ATP5F1 interacts_with PPARG
ATP5F1 interacts_with PARK7
ATP5F1 interacts_with BACE1
AGING interacts_with ATP5F1
NEURODEGENERATIVE DISEASES interacts_with ATP5F1

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