gene 876 words KG: PSMA3
Contents

PSMA3 Gene

🧬 Gene Info
Gene SymbolPSMA3
Full NameProteasome 20S Subunit Alpha 3
Chromosome14q23.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight28.1 kDa
Amino Acids255 aa
PathwaysAutophagy, Proteasome
NCBI Gene ID5684
Ensembl IDENSG00000172863
GeneCardsPSMA3
Human Protein AtlasPSMA3
Associated DiseasesALS, Alzheimer, dementia, neurodegeneration
InteractionsACTB, ACTG1, ATP5A1, CCT2, CDC42, EGFR
KG Connections69 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (15)

Parkinson Basal Ganglia Circuit
circuit · KG edge: therapeutic_target
GFAP (Redirect)
redirect · KG edge: interacts_with
Genes
index · KG edge: interacts_with
ACTB Gene
gene · KG edge: interacts_with
ACTG1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

CCT2 interacts_with PSMA3
GFAP interacts_with PSMA3
GRIA1 interacts_with PSMA3
SNAP25 interacts_with PSMA3
ACTG1 interacts_with PSMA3
SNCA interacts_with PSMA3
GAPDH interacts_with PSMA3
MAPK1 interacts_with PSMA3
PSMA3 interacts_with SOX2
PSMA3 interacts_with YWHAZ

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