gene 2,014 words KG: PKC
Contents

PRKCA Gene

🧬 Gene Info
Gene SymbolPKC
Full NameProtein Kinase C Alpha
Chromosome17q24.2
Protein FamilyPKC (Protein Kinase C) family
Amino Acids672 aa
Exons17
PathwaysAkt, Apoptosis, Autophagy, Complement, Differentiation
UniProt ID[P17252](https://www.uniprot.org/uniprot/P17252)
Ensembl IDENSG00000154229
OMIM176960
GeneCardsPKC
Human Protein AtlasPKC
Associated DiseasesAls, Alzheimer, Ataxia, Diabetes, Ms
Known Drugs/Compoundsmetformin
InteractionsAGING, AKT, ALOX5, AMPK, Amyloid, AMYLOID
KG Connections526 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (25)

Nucleolar Stress Response Normalization
Score: 0.65
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
Piezoelectric Nanochannel BBB Disruption
Score: 0.52
Optogenetic Control of Mitochondrial Transfer Networks
Score: 0.48
← Prevpg 2/2

Related Analyses (10)

Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (9)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: inhibits
Astrocytes
entity · KG edge: interacts_with
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: interacts_with

Knowledge Graph (12 edges)

PKC activates NRF2
PKC associated_with PRKCG
EEF2 activates PKC
PKC activates TNF
PKC activates FYN
PKC activates KEAP1
PKC activates CUL3
PKC activates BACH1
PKC associated_with MTOR
PKC inhibits ANG

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