| Gene Symbol | PALB2 |
| Full Name | Partner And Localizer of BRCA2 |
| Chromosome | 16p12.2 |
| Function | encodes a critical DNA repair protein that serves as a central hub in the Fanconi anemia pathway and homologous recombination repair. |
| Molecular Weight | 130 kDa |
| Amino Acids | 1186 aa |
| Ensembl ID | ENSG00000083093 |
| GeneCards | PALB2 |
| Human Protein Atlas | PALB2 |
| FA core complex | PALB2 interacts with the FA core complex |
| ID complex | Works with FANCD2-I (FANCI) for downstream signaling |
| BRCA complex | Part of the BRCA1-PALB2-BRCA2-RAD51 complex |
| Crosslink repair | Essential for interstrand crosslink repair |
| Associated Diseases | Cancer |
| Interactions | BRCA1, DNA, RAD18, UBIQUITIN |
| KG Connections | 56 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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