gene 612 words KG: NSF
Contents

NSF Gene

🧬 Gene Info
Gene SymbolNSF
Full NameN-Ethylmaleimide Sensitive Fusion Protein
Chromosome17q21.31
FunctionNSF is a member of the AAA+ (ATPases Associated with diverse cellular Activities) protein family that functions as a molecular chaperone for SNARE complex recycling
Primary Expressionall eukaryotic cells, with high expression in neurons - Protein Complexes: Forms hexameric complexes and interacts with alpha
Molecular Weight66 kDa
PathwaysApoptosis, Cell Cycle
UniProt IDP46459
NCBI Gene ID4900
Ensembl IDENSG00000134574
OMIM163580
GeneCardsNSF
Human Protein AtlasNSF
Associated Diseasesepilepsy
Known Drugs/Compoundsrapamycin
InteractionsAMPK, AND, LC3, MAP1LC3, MTOR, MTORC1
KG Connections109 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (17)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.81
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67

Related Analyses (9)

Astrocyte Reactivity Subtypes in Neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Mitochondrial transfer between neurons and glia
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (12)

Apoptosis in Neurodegeneration
entity · KG edge: regulates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
Genes
index · KG edge: biomarker_for
ATG12 — Autophagy Related 12
gene · KG edge: associated_with
CD8 Gene
gene · KG edge: biomarker_for

Knowledge Graph (12 edges)

VAMP8 associated_with NSF
ULK1 associated_with NSF
LC3 associated_with NSF
MCOLN1 associated_with NSF
GAPDH associated_with NSF
SQSTM1 associated_with NSF
NSF associated_with LAMP1
NSF associated_with ATG12
P62 associated_with NSF
NSF associated_with GAPDH

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