gene 1,927 words KG: MAF
Contents

MAF - MAFA BZIP Transcription Factor

🧬 Gene Info
Gene SymbolMAF
Full NameMAFA BZIP Transcription Factor[@yoshida2012]
Chromosome16q22.1
Protein TypeTranscription Factor
Functionis a member of the MAF family of transcription factors, belonging to the larger AP-1 superfamily of basic leucine zipper (bZIP) proteins.
Molecular Weight42 kDa
Amino Acids370 aa
PathwaysCo-inhibitory Gene Module, Endocytosis
UniProt IDQ9UHV9
NCBI Gene ID4094
Ensembl IDENSG00000185340
OMIM610266
GeneCardsMAF
Human Protein AtlasMAF
Associated DiseasesAls, Alzheimer, Atherosclerosis, Autoimmune, Cancer
InteractionsABCA7, AKT, APOPTOSIS, ATP, BRAF, CANCER
KG Connections190 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.71
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
Experiment: Multi-Ethnic PD GWAS
clinical · proposed · Score: 0.40
CRISPR Gene Correction Approaches for CBS/PSP
clinical · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40

See Also (12)

ATP P2X3 Receptor Neurons
cell · KG edge: activates
ABCA7 (Redirect)
redirect · KG edge: associated_with
Apoptosis in Neurodegeneration
entity · KG edge: activates
ATF6 - Activating Transcription Factor 6
gene · KG edge: associated_with
BMP7 Gene (Bone Morphogenetic Protein 7)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MAF inhibits CD8
MAF inhibits CD4
MAF inhibits PRDM1
MAF regulates C1Q
C1Q regulates MAF
MAF activates KEAP1
MAF activates NRF2
MAF activates P62
GAIN therapeutic_target MAF
MAF interacts_with NRF2

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