gene 699 words KG: JUNB
Contents

JUNB Gene

🧬 Gene Info
Gene SymbolJUNB
Chromosome19p13.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight35 kDa
Exons3 coding exons
PathwaysMAPK, Wnt
Ensembl IDENSG00000171223
GeneCardsJUNB
Human Protein AtlasJUNB
LocationChromosome 19p13.2
Gene Length~4.5 kb
Alternative SplicingSingle isoform
Associated DiseasesAtherosclerosis, Diabetes, Ms
Known Drugs/Compoundspokeweed mitogen
InteractionsC-FOS, C-JUN, FOS, FOSB, IL8, JUN
KG Connections94 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Circadian Clock-Autophagy Synchronization
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Temporal Decoupling via Circadian Clock Reset
Score: 0.54
Blood-Brain Barrier SPM Shuttle System
Score: 0.53

Related Analyses (5)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Apoptosis in Neurodegeneration
entity · KG edge: biomarker_for
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
Genes
index · KG edge: biomarker_for
ARNT - Aryl Hydrocarbon Receptor Nuclear Translocator
gene · KG edge: regulates
BMAL1 (ARNTL) Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

BMAL1 regulates JUNB
JUNB activates M1_MACROPHAGE
JUNB regulates CLOCK
JUNB regulates ARNT
pokeweed mitogen activates JUNB
CLOCK regulates JUNB
JUNB regulates AKT
JUNB activates TGFB1
TRAF6 biomarker_for JUNB
P38 biomarker_for JUNB

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