gene 754 words KG: IL7R
Contents

IL7R Gene - Interleukin-7 Receptor Alpha Chain

🧬 Gene Info
Gene SymbolIL7R
Full NameInterleukin-7 Receptor Alpha Chain
AliasesPage for IL7R Gene
Chromosome5p13.2
FunctionThe IL-7 receptor plays critical roles in immune system development and function
Primary ExpressionT cells, B cells, brain (neurons, microglia)
Amino Acids439 aa
Exons8
UniProt IDP16871
NCBI Gene ID3575
Ensembl IDENSG00000168685
OMIM146661
GeneCardsIL7R
Human Protein AtlasIL7R
Associated DiseasesFibrosis, Inflammation, Ms
InteractionsABL1, ABL2, App, CRLF2, CSF1R, CXCR4
KG Connections115 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (12)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
APOE-TREM2 Interaction Modulation
Score: 0.74
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58
TREM2-Dependent Microglial Senescence Transition
Score: 0.58

Related Analyses (8)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (11)

CCL4 Gene
gene · KG edge: associated_with
CCL5 — C-C Motif Chemokine Ligand 5
gene · KG edge: associated_with
CDK1 — Cyclin-Dependent Kinase 1
gene · KG edge: associated_with
CSF1R — Colony Stimulating Factor 1 Receptor
gene · KG edge: activates
CXCL10 - C-X-C Motif Chemokine Ligand 10
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TYK2 contributes_to IL7R
PTK2B contributes_to IL7R
IL7R contributes_to JAK2
IL7R contributes_to NTRK3
IL7R contributes_to CSF1R
NTRK3 contributes_to IL7R
PDGFRB contributes_to IL7R
JAK2 contributes_to IL7R
CXCL8 associated_with IL7R
CCL4 associated_with IL7R

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.