| Gene Symbol | DOCK2 |
| Full Name | Dedicator of cytokinesis protein 2 |
| Aliases | Dedicator of cytokinesis 2 |
| Chromosome | 5q33.3 |
| Function | is a member of the DOCK family of guanine nucleotide exchange factors (GEFs) that specifically activates the small GTPase RAC1. |
| Primary Expression | hematopoietic cells, including lymphocytes, macrophages, and dendritic cells, where it plays essential roles in cell migration, adhesion, and activati |
| Subcellular Localization | the leading edge of migrating cells where PI3K activity is highest |
| Molecular Weight | 215 kDa |
| Amino Acids | 970 aa |
| Exons | 48 |
| UniProt ID | Q8JY91 |
| NCBI Gene ID | 1765 |
| Ensembl ID | ENSG00000074584 |
| OMIM | 601059 |
| GeneCards | DOCK2 |
| Human Protein Atlas | DOCK2 |
| Associated Diseases | Ataxia, Ms, Parkinson |
| Interactions | CSF1R |
| KG Connections | 52 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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