gene 1,267 words KG: CCL4
Contents

CCL4 Gene

🧬 Gene Info
Gene SymbolCCL4
Full NameC-C motif chemokine ligand 4
Chromosome17q12
Functionis a member of the CC chemokine family that plays critical roles in immune cell recruitment and neuroinflammation.
Molecular Weight10 kDa
Amino Acids92 aa
Exons3
PathwaysPI3K, MAPK, NF-κB pathway
NCBI Gene ID6351
Ensembl IDENSG00000129277
GeneCardsCCL4
Human Protein AtlasCCL4
Associated DiseasesAging, Als, Cancer, Fibrosis, Inflammation
InteractionsAKT, Albumin, AND, App, AUTOPHAGY, CCL2
KG Connections173 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62

Related Analyses (5)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
C1QA Gene
gene · KG edge: associated_with
C1QB — Complement Component 1Q Beta
gene · KG edge: associated_with
CCL3 Gene
gene · KG edge: activates
Autoimmune Hypothesis in Alzheimer's Disease
hypothesis · KG edge: activates

Knowledge Graph (12 edges)

FOXO1 activates CCL4
PI3K activates CCL4
AKT activates CCL4
CCL4 activates FOXO1
CCL4 activates PI3K
CCL4 therapeutic_target LC3
CCL4 activates MTOR
CCL4 activates CCR5
CCL5 activates CCL4
CCL4 activates CCL3

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