gene 1,032 words KG: EMD
Contents

EMD — Emerin

🧬 Gene Info
Gene SymbolEMD
Full NameEmerin
ChromosomeXq28
FunctionThe EMD gene encodes emerin, a 34-kDa integral membrane protein of the inner nuclear envelope.
Primary ExpressionSkeletal Muscle, Cardiac Muscle, Nuclear Envelope
PathwaysMAPK signaling, apoptosis pathway, autophagy pathway, necroptosis, oxidative stress response
UniProt IDP50402
NCBI Gene ID2010
Ensembl IDENSG00000102119
OMIM300384
GeneCardsEMD
Human Protein AtlasEMD
Associated DiseasesAD, ALI, Als, Alzheimer, Autoimmune
InteractionsABCD3, Actin, ALS, ALZHEIMER, ALZHEIMER DISEASE, AMBRA1
KG Connections420 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (8)

APOE-Dependent Autophagy Restoration
Score: 0.85
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
Aquaporin-4 Polarization Rescue
Score: 0.73
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72

Related Analyses (4)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (12)

ATP P2X3 Receptor Neurons
cell · KG edge: interacts_with
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: interacts_with
Apoptosis in Neurodegeneration
entity · KG edge: co_discussed
ABCD3 Gene
gene · KG edge: interacts_with
AMBRA1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

CAT interacts_with EMD
OPTN interacts_with EMD
DNM1L interacts_with EMD
CANX interacts_with EMD
LGALS3 interacts_with EMD
CALCOCO2 interacts_with EMD
G3BP1 interacts_with EMD
PEX3 interacts_with EMD
SQSTM1 interacts_with EMD
BCL2 interacts_with EMD

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